Yaobitong Capsules Efficacy and Safety Review: Meta-Analysis of 17 RCTs

Shi-Ao Wang authored a systematic review and meta-analysis evaluating the efficacy and safety of Yaobitong capsules for lumbar disc herniation. The analysis includes 17 randomized controlled trials involving 1,752 patients, with literature searched up to October 31, 2025. The supplementary file contains the full review document, including methodology, results, and conclusions.

Use Cases

• Conducting a secondary analysis of the meta-analysis results based on the reported statistical outcomes
• Reviewing the methodology for systematic reviews of traditional Chinese medicine based on the described search and evaluation protocols
• Assessing the quality of clinical trial reporting based on the application of the Cochrane Risk of Bias tool and GRADE approach

Strengths

• Analysis is based on 17 randomized controlled trials, providing a multi-study evidence base
• The review employed comprehensive quality assessment using the Cochrane Risk of Bias tool and GRADE framework
• The document reports specific quantitative outcomes, including mean differences for VAS, ODI, and JOA scores with confidence intervals

Limitations

• The dataset is a single supplementary document file; the underlying trial data are not provided
• Column-level documentation is absent; field semantics must be inferred after download
• The authors note most included trials were small, single-center studies conducted in China, which may limit generalizability

Provenance

Source

figshare

Collection Method

Systematic literature review and meta-analysis of published randomized controlled trials.

Time Range

Literature searched from database inception up to 31 October 2025.

Freshness

Last updated 2026-06-01 04:17:29

Geography

The included trials were primarily conducted in China.