Common Carp Cathepsin L Gene Expression Profiles Across Tissues and Infection

Nine cathepsin L paralog genes were identified in the polyploid common carp, revealing tissue-specific expression patterns. Data includes expression levels across tissues, immune compartments, and during infection with the pathogen Sphaerospora molnari. Sagar Nayak published this dataset on figshare in April 2026.

Use Cases

• Classify tissue type (e.g., mucosal barrier vs. head kidney) based on ctsl.1A/B and ctslaA/B paralog expression levels.
• Model the temporal dynamics of ctsl gene expression reprogramming during Sphaerospora molnari infection progression.
• Predict structural variations in protease loop architecture using paralog sequence data from the nine retained duplicates.
• Analyze the correlation between inflammatory cytokine induction and ctsl transcript downregulation across different cell types.

Strengths

• Identifies nine distinct cathepsin L (ctsl) paralogs retained from duplication events.
• Expression data is partitioned across specific tissues and immune compartments like blood and head kidney leukocytes.
• Includes temporal data on gene expression changes during a defined pathogen infection.

Limitations

• Dataset scale is limited at 27.0 MB, suggesting a constrained sample or feature count.
• The exact row count and column names are unknown, limiting immediate assessment of data structure.
• Data is specific to the common carp model, limiting direct applicability to other vertebrate systems.

Provenance

Source

figshare, authored by Sagar Nayak.

Collection Method

Gene identification and expression profiling from the common carp model, likely via sequencing and qPCR.

Time Range

Covers the progression of Sphaerospora molnari infection, but specific dates are not provided.

Freshness

Last updated in April 2026.

Geography

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