WIN-1001X: Mouse Model Data on Botanical Extract Efficacy for Diabetic Wound Healing

Supplementary file 1 contains research data on the effects of a 3% WIN-1001X cream, an extract of three botanical drugs, on chronic skin wounds in streptozotocin-induced diabetic mice. The study, authored by Hayan Jeong and last updated in March 2026, measured wound area, histology, and gene/protein expression related to inflammation and healing over a 12-day treatment period. The dataset is a 3.1 MB DOCX file shared under a CC-BY-4.0 license on figshare.

Use Cases

• Modeling the relationship between botanical extracts and wound area reduction based on daily measurements over 12 days.
• Analyzing gene expression patterns for pro-inflammatory cytokines and growth factors like PDGFβ, HGF, KGF, and TGFβ.
• Studying macrophage polarization (M1 to M2) and immune cell infiltration in a diabetic wound healing context.
• Investigating correlations between anti-microbial peptide activation and wound healing outcomes.

Strengths

• The experimental protocol is explicitly detailed, including the 12-day treatment period and specific measurements taken.
• Research focuses on a defined chronic wound model (streptozotocin-induced diabetic mice) and a specific compound (3% WIN-1001X cream).

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for quantitative analysis.
• The data is contained within a DOCX file, which may require parsing to extract structured information.

Provenance

Source

Hayan Jeong via figshare.

Collection Method

Data generated from a laboratory study on diabetic mice, involving wound creation, topical treatment, and molecular/histological analysis.

Time Range

The study period is not specified, but data reflects a 12-day experimental timeline.

Freshness

Last updated 2026-03-18 10:08:03; freshness should be verified.

Geography

Spatial coverage is not specified.