Ceratocarpus Arenarius Polysaccharide Extraction and Anti-Inflammatory Activity

Junlong Wang's research, published on figshare in March 2026, details the extraction and chemical modification of polysaccharides from the plant Ceratocarpus arenarius L. The work includes optimization of extraction conditions yielding 19.09% crude polysaccharide and structural analysis of a purified fraction and its derivatives. The study characterizes the anti-inflammatory effects of these compounds by measuring their impact on nitric oxide and cytokine production.

Use Cases

• Training models to predict polysaccharide yield based on extraction parameters like time, power, and temperature.
• Analyzing relationships between chemical modification (carboxymethylation, sulfation) and changes in molecular weight or solubility.
• Correlating structural features like glycosidic bond types with bioactivity metrics such as nitric oxide suppression.
• Benchmarking experimental results for polysaccharide extraction and characterization against a published methodology.

Strengths

• Includes specific, optimized extraction parameters (e.g., 43 min, 310 W, 21:1 mL/g ratio) with a reported yield of 19.09%.
• Describes a multi-technique structural characterization approach using FT-IR, NMR, and chromatography.
• Bioactivity is quantified against multiple inflammatory markers (NO, PGE2, IL-6, IL-1β, TNF-α).

Limitations

• The primary data format is a DOCX document (2.4 MB); structured, machine-readable data (e.g., raw numerical results) is not explicitly provided.
• Row count and column-level documentation are unknown, which may limit suitability assessment for direct computational analysis.
• Description metadata is limited; actual data quality and completeness require manual inspection after download.

Provenance

Source

figshare, authored by Junlong Wang.

Collection Method

Laboratory research involving response surface methodology optimization, column chromatography, spectroscopic analysis, and in vitro anti-inflammatory assays.

Freshness

Last updated 2026-03-18 07:44:08; freshness should be verified.