Safety and Survival Outcomes from Four Perioperative Drug Trials in Cancer Patients

Data from four randomized controlled trials involving 148 patients with breast, colorectal, and pancreatic cancers. The dataset, authored by Nahida Sakis and last updated in April 2026, reports safety and long-term survival outcomes for a perioperative regimen of propranolol and etodolac.

Use Cases

• Analyzing adverse event rates for perioperative drug combinations based on reported safety outcomes.
• Modeling long-term disease-free survival based on the 8-year follow-up data mentioned in the description.
• Comparing biomarker changes across cancer types based on the reported blood indices.
• Assessing the feasibility of perioperative treatment protocols based on the detailed dosing schedule.

Strengths

• Includes data from four distinct randomized controlled trials, providing a multi-study perspective.
• Reports on 148 patients across three cancer types (breast, colorectal, pancreatic).
• Contains long-term follow-up data with 8-year disease-free and overall survival outcomes.
• Clinical trial registration identifiers are provided for verification.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small (229.1 KB), indicating limited scope and likely summary-level data.

Provenance

Source

figshare

Collection Method

Data collected from four randomized controlled trials.

Time Range

Perioperative period with 8-year survival follow-up.

Freshness

Last updated 2026-04-20 05:22:54; freshness should be verified.

Geography

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