Multi-Omics Analysis of Walnut Meal Substitution Effects on Diqing Tibetan Pigs

A 3.0 MB supplementary document by Xinpeng Li, last updated March 2026, details a study on replacing soybean meal with walnut meal in pig diets. The research uses integrated metagenomics, transcriptomics, and lipidomics to analyze effects on fat deposition. Findings indicate a 50% substitution ratio reduces backfat thickness and increases intramuscular fat content.

Use Cases

• Study the effects of walnut meal substitution on subcutaneous and intramuscular fat based on the described multi-omics analysis.
• Analyze relationships between gut microbiota (e.g., Clostridium butyricum) and fat metabolism in pigs based on the described metagenomic findings.
• Investigate gene expression changes (e.g., MEDAG, VDR, PPARGC1A) related to adipocyte differentiation and triglyceride synthesis based on the transcriptomics results.
• Model lipidomic pathways involving metabolites like acylcarnitines and free fatty acids based on the described mechanisms.

Strengths

• Data is derived from an integrated multi-omics analysis including metagenomics, transcriptomics, and lipidomics.
• Study reports statistically significant results (P < 0.05) for key outcomes like backfat thickness and intramuscular fat.
• Dataset is openly available under a CC-BY-4.0 license.

Limitations

• The primary data file is a 3.0 MB DOCX document; underlying raw datasets (e.g., sequence reads, lipid profiles) are not directly accessible.
• Row count and column-level documentation for any underlying tabular data are unknown.
• The study focuses specifically on Diqing Tibetan pigs, which may limit generalizability to other breeds or regions.

Provenance

Source

figshare, authored by Xinpeng Li.

Collection Method

Experimental study on Diqing Tibetan pigs, with data generated via integrated multi-omics analyses.

Freshness

Last updated 2026-03-19 06:31:18.

Geography

Diqing region, Qinghai-Tibet Plateau, China.