Sepsis-Associated Thrombocytopenia Patient Vital Sign Trajectories and Blood Gas Ranges

Supplementary file 1 contains data and analysis from a retrospective study using the MIMIC-IV database. The dataset likely includes hourly vital sign trajectories for sepsis-associated thrombocytopenia patients during their first 12 hours in the ICU, along with derived blood gas parameter ranges. The author is Shihao Jin, and the file was last updated on 2026-04-09.

Use Cases

• Identify high-risk patient subgroups based on early vital sign trajectories mentioned in the description
• Analyze nonlinear relationships between blood gas parameters and ICU mortality risk for sepsis-associated thrombocytopenia
• Define exploratory physiological reference ranges for pH, PO2, PCO2, lactate, base excess, and total CO2
• Apply group-based multi-trajectory modeling to hourly ICU data for patient clustering

Strengths

• Derived specific blood gas ranges associated with lowest predicted mortality risk (e.g., pH 7.32–7.64)
• Identified three distinct patient clusters with quantified mortality hazard ratios (HR 1.40 for ICU mortality)
• Data sourced from the MIMIC-IV database, a known clinical data repository

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• The dataset is a 791.4 KB PDF, which is a tiny dataset and may contain only summary results rather than raw data

Provenance

Source

MIMIC-IV database

Collection Method

Retrospective study using group-based multi-trajectory modeling and restricted cubic spline analysis

Freshness

Last updated 2026-04-09 05:20:05; freshness should be verified