FUT4 Peptide-CNT Nanovaccine Data for Ovarian Cancer Mouse Model

A 12.1 MB supplementary document from a study evaluating fucosyltransferase 4 (FUT4) peptide-conjugated carbon nanotubes as a nanovaccine in an immunocompetent ID8-Defb29/Vegf-a ovarian cancer mouse model. The research, authored by J. J. Guzmán-Mendoza and shared under a CC-BY-4.0 license on figshare, includes immune profiling, RNA sequencing, and survival data from C57BL/6 mice. The dataset was last updated on 2026-05-19.

Use Cases

• Evaluate nanocarrier efficacy for antigen delivery based on immune profiling data mentioned in the description
• Analyze gene expression changes in ascites-derived cells based on exploratory RNA sequencing results
• Study correlations between immune cell infiltration and disease progression based on bioluminescence imaging and survival data
• Compare humoral and cellular immune responses across different immunization strategies described in the study

Strengths

• Data is associated with a specific, well-defined immunocompetent mouse model (ID8-Defb29/Vegf-a) for ovarian cancer
• Includes multiple experimental readouts such as flow cytometry, confocal microscopy, RNA sequencing, and bioluminescence imaging
• Shared under a permissive CC-BY-4.0 license allowing for reuse and redistribution

Limitations

• The primary data file is a 12.1 MB DOCX document, which may require extraction and formatting for computational analysis
• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment

Provenance

Source

figshare

Collection Method

Experimental data generated from a preclinical study in a murine ovarian cancer model.

Freshness

Last updated 2026-05-19 05:38:39; freshness should be verified