Functional Characterization of Urine-Derived Stem Cells from ACLF Patients

A supplementary document describes a preclinical study evaluating urine-derived stem cells from acute-on-chronic liver failure patients. The research, authored by Jiateng Zhang, assesses the cells' therapeutic and immunomodulatory potential in a mouse model of immune-mediated acute liver injury. The dataset was last updated on April 17, 2026.

Use Cases

• Analyze the therapeutic efficacy of stem cell transplantation based on survival analysis and serum biochemical parameters mentioned in the description.
• Study immunomodulatory mechanisms based on inflammatory cytokine profiling and macrophage-associated signature data referenced in the description.
• Evaluate histological outcomes of liver tissue repair based on the hepatocellular necrosis assessment described in the methods.

Strengths

• Dataset is shared under a permissive CC-BY-4.0 license, facilitating reuse.
• The description provides specific methodological details, including the use of a Concanavalin A-induced mouse model and hydrogel encapsulation.

Limitations

• The dataset is a 4.1 MB DOCX file, which is a small and unstructured text format requiring manual extraction of data.
• Column-level documentation and sample data are unavailable, making field semantics and data structure unclear.
• Row count is unknown, which may limit suitability assessment for quantitative analysis.

Provenance

Source

figshare

Collection Method

Likely contains experimental data and analysis from a preclinical study, as described in the document.

Freshness

Last updated 2026-04-17 05:21:33; freshness should be verified.