DIRECT-MT Trial: Health-Related Quality of Life After Stroke Thrombectomy

656 patients from the DIRECT-MT trial provide data comparing health-related quality of life outcomes between two stroke treatment strategies. The dataset includes EQ-5D-5L index scores at 90 days, analyzed by baseline stroke severity and functional outcome strata. Renjun Gu authored this secondary analysis, with data last updated in May 2026.

Use Cases

• Compare health-related quality of life outcomes based on treatment strategy (direct endovascular thrombectomy vs. bridging therapy).
• Analyze the effect modification of baseline stroke severity on treatment outcomes.
• Investigate associations between functional outcome strata (e.g., Barthel Index, modified Rankin Scale) and quality of life dimensions.
• Model patient-centered outcomes for different baseline severity categories.

Strengths

• Data originates from a randomized controlled trial (DIRECT-MT) with 656 patients.
• Includes patient-reported outcome measures (EQ-5D-5L index) collected at a standardized 90-day follow-up.
• Analysis incorporates interaction terms for baseline severity and exploratory functional strata.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data is contained in a DOCX file, which may require conversion for analysis.

Provenance

Source

Secondary analysis of the DIRECT-MT trial.

Collection Method

Clinical trial data collection and analysis.

Freshness

Last updated 2026-05-25 04:32:57; freshness should be verified.