A median follow-up of 16.2 years from a prospective cohort study of 26,585 UK Biobank participants. The document contains results investigating how dietary quality modifies the association between peripheral monocyte counts and incident cardiovascular disease, authored by Xueguang Lin and last updated in May 2026.
Use Cases
- Analyze the interaction between dietary patterns and immune cell counts on disease risk based on the described Diet Quality Index.
- Investigate proteomic mechanisms linking diet and inflammation based on the identified protein REG4.
- Validate statistical models for joint risk assessment based on the described Cox proportional hazards and restricted cubic spline methods.
Strengths
- 26,585 participants provide a substantial cohort size.
- Median follow-up of 16.2 years offers long-term observational data.
- Results include specific hazard ratios and confidence intervals (e.g., HR: 1.28, 95% CI: 1.11–1.48).
Limitations
- The dataset is a 119.0 KB DOCX file, suggesting limited scope and likely containing summary results rather than raw data.
- Column-level documentation is absent; field semantics must be inferred after download.
- The proteomic finding for REG4 is noted as exploratory and did not survive multiple testing correction.
Provenance
- Source
- UK Biobank
- Collection Method
- Prospective cohort study with blood measurements and dietary assessments.
- Time Range
- Median follow-up of 16.2 years.
- Freshness
- Last updated 2026-05-26 05:25:58.
- Geography
- United Kingdom