Interoceptive Dysfunction in Schizophrenia: Protocol for a Multimodal MRI Study

A research protocol for a cross-sectional study comparing 30 individuals with schizophrenia and 30 healthy controls. The study, authored by Peipei Luan, involves behavioral interoceptive tasks, clinical symptom ratings, cognitive testing, and multimodal MRI scanning. The protocol was last updated on 2026-04-17.

Use Cases

• Analyzing correlations between interoceptive accuracy and clinical symptom severity based on PANSS, HAM-A, and HAM-D scores.
• Investigating neural connectivity patterns within interoception-related circuits based on resting-state fMRI and DTI data.
• Comparing structural brain abnormalities in thalamo-cortical pathways between patient and control groups based on T1-weighted imaging.
• Modeling relationships between subjective interoceptive awareness and cognitive performance based on MAIA, BPQ, and cognitive test results.

Strengths

• The protocol outlines a multimodal assessment combining behavioral, clinical, cognitive, and neuroimaging data.
• The study design includes a matched control group of 30 healthy individuals for comparison with 30 patients.
• The protocol is openly licensed under CC-BY-4.0, facilitating reuse and sharing.

Limitations

• The dataset is a 143.2 KB protocol document; the actual research data is not included, limiting immediate analysis.
• Column-level documentation for any resulting data is absent; field semantics must be inferred after download.
• The row count for any future dataset is unknown, which may limit suitability assessment.

Provenance

Source

figshare, authored by Peipei Luan.

Collection Method

The description details a planned cross-sectional study protocol for data collection.

Freshness

Last updated 2026-04-17 05:21:34; freshness should be verified.