Licochalcone A and Cisplatin Nephrotoxicity: Supplementary Research File

A 3.0 MB DOCX file uploaded to figshare by Mo Han on April 17, 2026. The file contains supplementary material for a study investigating Licochalcone A's protective effects against cisplatin-induced kidney damage. The research employed in vivo murine models and in vitro HK-2 cell assays.

Use Cases

• Reviewing detailed experimental methods for in vivo and in vitro models of cisplatin nephrotoxicity.
• Analyzing results from assays measuring ferroptosis markers like Fe2+, GSH, and lipid peroxidation.
• Examining mechanistic data from molecular docking, cellular thermal shift assays, and Nrf2-knockdown studies.
• Referencing metabolomic analysis findings on energy metabolism and glutathione homeostasis.

Strengths

• File size is precisely 3.0 MB.
• License is clearly stated as CC-BY-4.0.
• The description provides a detailed account of the experimental methods and key findings.

Limitations

• The exact data format and structure within the DOCX file are unknown.
• Row count and column-level documentation are absent.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Likely contains supplementary data generated from the described laboratory experiments.

Freshness

Last updated 2026-04-17 05:08:41; freshness should be verified.