Fecal Shedding of Antibiotic-Resistant Bacteria in Dairy Cows After Systemic Treatment

A randomized clinical trial from 2026 by Juliano L. Gonçalves evaluated the long-term effects of systemic ceftiofur and ampicillin on resistant Gram-negative bacteria in healthy dairy cows. Fecal samples were collected from 24 cows over 12 weeks, with bacterial abundance enumerated on selective agar. The study found minimal changes in the proportion of resistant bacteria after antibiotic treatment.

Use Cases

• Modeling the duration of resistant bacteria shedding in feces based on weekly sampling over 11 weeks.
• Analyzing the effect of systemic antibiotic treatments on fecal microbiota based on the described clinical trial design.
• Studying the relative abundance of antimicrobial resistance gene classes, such as MLS and beta-lactams, mentioned in the results.

Strengths

• Data originates from a controlled randomized clinical trial with 8 cows per treatment group.
• Sampling occurred weekly for 11 weeks, providing a longitudinal view of bacterial shedding.
• The dataset is openly available under a CC-BY-4.0 license.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small (183.1 KB), indicating limited scope, likely containing summary results or a supplementary document.

Provenance

Source

figshare

Collection Method

Fecal samples were collected from healthy lactating Holstein cows, diluted, and inoculated on selective agar for bacterial enumeration.

Time Range

Samples were collected weekly over an 11-week period following a 5-day treatment.

Freshness

Last updated 2026-04-30 14:30:38; freshness should be verified.

Geography

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