Supplementary file 1_Low-dose rocuronium as an adjuvant to remifentanil for laryngeal mask

A study protocol for a randomized, double-blind, placebo-controlled trial involving 140 children aged 1–6 years. The trial investigates the effect of low-dose rocuronium as an adjuvant during laryngeal mask airway-assisted flexible fiberoptic bronchoscopy under general anesthesia. The protocol was authored by Shang-xian Xu and last updated on 2026-05-08.

Use Cases

• Analyzing the effect of neuromuscular blockade on coughing frequency during pediatric bronchoscopy based on the primary endpoint described.
• Comparing cumulative remifentanil dosage between intervention and control groups based on the secondary endpoints listed.
• Evaluating procedure success rates and stakeholder satisfaction scores based on the secondary outcome measures.
• Studying hemodynamic stability and adverse event profiles in a pediatric anesthesia setting based on the described endpoints.

Strengths

• The protocol is for a randomized, double-blind, placebo-controlled trial, a rigorous study design.
• The trial includes 140 pediatric participants with a clear age range of 1–6 years.
• The protocol lists 10 specific secondary endpoints, including quantitative and qualitative measures.
• The study is registered with a public identifier (ChiCTR2500105407) on a clinical trials registry.

Limitations

• The dataset is a 69.9 KB DOCX protocol document; the underlying trial data is not included.
• Column-level documentation for the trial's raw data is absent; field semantics must be inferred from the protocol.
• Row count for the trial's results data is unknown, which may limit suitability assessment for direct analysis.

Provenance

Source

figshare, authored by Shang-xian Xu.

Collection Method

Described as a planned randomized controlled trial.

Time Range

Temporal coverage of the planned trial is not specified.

Freshness

Last updated 2026-05-08 05:48:04; freshness should be verified as the date is in the future.

Geography

Spatial coverage is not explicitly stated in the provided metadata.