Supplementary file 1_Micro-osteoperforation for accelerating orthodontic tooth movement: a

A 2026 meta-analysis by Shu-Hong Ching synthesizes data from 16 randomized controlled trials (RCTs) sourced from PubMed, Web of Science, and other databases. It evaluates the short-term efficacy and safety of micro-osteoperforation (MOPs) as an adjunct to orthodontic treatment. The analysis includes 1,175 screened records and reports quantitative outcomes on tooth movement acceleration and adverse effects.

Use Cases

• Evaluating the acceleration effect of MOPs on orthodontic tooth movement based on reported mean differences in movement distance.
• Assessing the safety profile of MOPs based on reported secondary outcomes like root resorption and periodontal parameter changes.
• Determining optimal clinical application parameters for MOPs based on subgroup analyses of factors like mandibular application, repetition, and device type.
• Informing clinical trial design for orthodontic interventions by referencing the included study characteristics and risk-of-bias assessment.

Strengths

• Analysis is based on 16 randomized controlled trials, providing a structured evidence base.
• Reports specific quantitative findings, such as a 0.67 mm increase in total tooth movement distance with 95% confidence intervals.
• Employs standardized assessment tools (Cochrane ROB 2, GRADE) for evaluating study quality and evidence certainty.

Limitations

• The primary data file is a 4.4 MB DOCX document; the underlying structured dataset (e.g., columns, rows) is not directly accessible.
• Row count and column-level documentation are unknown, limiting suitability assessment for direct computational analysis.
• Focus is explicitly on short-term outcomes; long-term effects and optimal parameters require further investigation as noted in the conclusions.

Provenance

Source

figshare

Collection Method

Systematic literature review and meta-analysis of published randomized controlled trials.

Freshness

Last updated 2026-05-14.