Systematic Review of Cartilage Repair Models Using Autologous MSCs on Scaffolds

Mikołaj Wróbel's review document, published on figshare in March 2026, assesses preclinical studies on cartilage repair strategies using autologous mesenchymal stem cells (MSCs) seeded on scaffolds in animal models. The 8.6 KB DOCX file synthesizes evidence on the regenerative potential of these therapies, particularly highlighting the efficacy of bone marrow-derived MSCs combined with biodegradable scaffolds. The review identifies key knowledge gaps, including a lack of standardized protocols and limited insight into long-term tissue maturation.

Use Cases

• Identify effective MSC sources and scaffold combinations for cartilage regeneration based on the review's synthesis.
• Design standardized experimental protocols for future studies based on the identified methodological gaps.
• Inform the selection of animal models and outcome measures for long-term cartilage repair studies based on the review's conclusions.

Strengths

• File is openly licensed under CC-BY-4.0.
• Focus is clearly defined on autologous MSCs and scaffolds for cartilage repair.
• Review identifies specific knowledge gaps, such as the need for studies longer than 2 years.

Limitations

• Dataset is a single 8.6 KB text document, offering limited scope for direct data analysis.
• Row count and column-level documentation are absent; the content is narrative.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare, author Mikołaj Wróbel

Collection Method

Systematic narrative review of preclinical studies.

Time Range

Review publication date is 2026; temporal coverage of included studies is unspecified.

Freshness

Last updated 2026-03-18 10:15:38; freshness should be verified.

Geography

Spatial coverage is unspecified.