Systematic Review of MRI-Guided Laser Therapy for Drug-Resistant Epilepsy

Carlos Quispe-Vicuña authored a systematic review overview of MRI-guided laser interstitial thermal therapy (MRgLITT) for drug-resistant epilepsy. The review analyzed 16 systematic reviews, reporting seizure freedom rates from 18.87% to 75.86% and complication rates such as visual field deficits (2.17%–7.5%). The document was last updated on 2026-05-29 and is licensed under CC-BY-4.0.

Use Cases

• Summarizing clinical evidence on seizure freedom rates for MRgLITT based on the reported range of 18.87% to 75.86%.
• Analyzing perioperative complication profiles based on reported rates for visual field deficits and intracranial hemorrhage.
• Assessing the quality of systematic reviews in this field based on the application of the AMSTAR-2 and GRADE tools mentioned in the description.

Strengths

• Includes a specific protocol registration number (CRD42022339024), indicating a predefined methodology.
• Reports specific outcome ranges, such as seizure freedom (18.87%–75.86%) and complication rates (e.g., visual field deficit 2.17%–7.5%).
• Evaluates the certainty of evidence using the standardized GRADE approach mentioned in the description.

Limitations

• The dataset is a 724.1 KB DOCX file, which is a small document rather than a structured data product.
• Row count and column-level documentation are absent; data semantics must be inferred from the narrative text.
• The description notes all outcomes reported a 'very low' certainty of evidence due to the absence of randomized studies.

Provenance

Source

figshare, author Carlos Quispe-Vicuña

Collection Method

Systematic review of systematic reviews, with searches in PubMed, Embase, Scopus, Web of Science, Cochrane Library, and Google Scholar up to May 30, 2024.

Time Range

Literature search covered studies up to May 30, 2024.

Freshness

Last updated 2026-05-29 06:18:53; freshness should be verified.