Murine Model Data on CPAP Treatment for Hyperoxia-Induced Lung Damage

A 2026 study by Jitendra K. Tripathi investigates non-invasive respiratory support in a mouse model of bronchopulmonary dysplasia. The dataset, shared via figshare, includes experimental findings on lung function parameters and histopathological changes. Results indicate treatment effects on compliance, airway resistance, and alveolar structure.

Use Cases

• Analyze the effect of CPAP on lung compliance and resistance based on reported Cst and Ers parameters
• Study correlations between hyperoxia exposure and alveolar simplification based on described Mean Linear Intercept (MLI) measurements
• Evaluate histopathological markers of lung injury and repair based on described septal thickening assessments

Strengths

• Includes statistically significant results (e.g., p=0.0416 for compliance, p<0.0001 for septal thickness)
• Released under a permissive CC-BY-4.0 license for reuse
• Focuses on a specific, clinically relevant murine model of bronchopulmonary dysplasia

Limitations

• Dataset is a single 47.5 KB DOCX file, suggesting limited raw data scope
• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment for quantitative analysis

Provenance

Source

figshare

Collection Method

Experimental study using a hyperoxia-induced murine model with histopathological and lung function analysis.

Time Range

2026

Freshness

Last updated 2026-04-20 05:19:30; freshness should be verified

Geography

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