Hemodynamic Simulation of Gonadal Vein in Nutcracker Syndrome, 57 Patients

A 2026 study by Yun-Hua Ji presents computational fluid dynamics (CFD) simulations and clinical measurements from 57 patients with Nutcracker syndrome and varicocele. The dataset likely contains numerical results from simulations modeling the hemodynamic effects of the Valsalva maneuver on the left renal and gonadal veins. It was published on figshare under a CC-BY-4.0 license.

Use Cases

• Training predictive models for venous reflux based on anatomical parameters like aortomesenteric angle and LRV diameter.
• Validating computational fluid dynamics simulations of vascular compression using clinical velocity and pressure measurements.
• Analyzing correlations between wall shear stress elevation and endothelial injury risk in stenotic veins.
• Studying the hemodynamic impact of intra-abdominal pressure changes on venous return and thrombogenesis.

Strengths

• Includes clinical data from 57 consecutively enrolled patients with specific anatomical and hemodynamic measurements.
• CFD simulations provide quantitative results, including a 12-fold increase in wall shear stress and a pressure gradient of approximately 7,600 Pa.
• Explicitly models a complete Valsalva cycle with a physiologically relevant time-varying pressure boundary condition.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The primary data file is a 2.2 MB DOCX document, which may require extraction of structured numerical data.

Provenance

Source

Yun-Hua Ji via figshare

Collection Method

Clinical data from Doppler ultrasonography and a 3D CFD model reconstructed from contrast-enhanced CT data.

Freshness

Last updated 2026-05-18 05:40:04; freshness should be verified.