Remote Ischemic Conditioning for Stroke: A Systematic Review and Meta-Analysis

Yushuo Liu's supplementary file contains the systematic review and meta-analysis on remote ischemic conditioning for acute ischemic stroke. The analysis includes 12 randomized controlled trials involving 5,301 patients, with data collected from inception to March 30, 2026. The document evaluates treatment efficacy and safety, focusing on the impact of treatment duration and reperfusion strategies.

Use Cases

• Analyzing the efficacy of remote ischemic conditioning based on functional independence outcomes at 90 days.
• Comparing treatment protocols based on the subgroup analysis of longer-duration (≥5 days) versus shorter-duration RIC.
• Evaluating the impact of reperfusion context based on outcomes for patients undergoing endovascular thrombectomy versus intravenous thrombolysis.
• Assessing the safety profile of RIC based on the analysis of 90-day mortality rates.

Strengths

• Analysis is based on 12 randomized controlled trials, a standard for clinical evidence.
• Includes data from 5,301 patients, providing a substantial sample size for a meta-analysis.
• Uses a defined search strategy across major databases (PubMed, Embase, Cochrane Library, Web of Science).
• Results include specific risk ratios and confidence intervals for primary and secondary outcomes.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is a 405.0 KB DOCX file, indicating a limited scope focused on a single review document.

Provenance

Source

Yushuo Liu via figshare

Collection Method

Systematic review and meta-analysis of randomized controlled trials.

Time Range

Literature search from database inception to March 30, 2026.

Freshness

Last updated 2026-05-19 04:20:46; freshness should be verified.