Supplementary file 1_Probiotic properties of Lactobacillus rhamnosus GL68 with cholesterol

A figshare document details an in vitro and in vivo study of the probiotic strain Lactobacillus rhamnosus GL68. The research, authored by Yurong Gao and last updated in June 2026, reports cholesterol-lowering rates of 71.2% and antioxidant scavenging rates over 79% in lab tests. The study also describes the strain's effects on Sprague-Dawley rats fed a high-fat diet, measuring changes in body mass, blood lipid levels, liver enzymes, and gut microbiota.

Use Cases

• Evaluating probiotic cholesterol-lowering efficacy based on in vitro assay results described in the document
• Studying antioxidant activity of bacterial strains based on DPPH and hydroxyl radical scavenging rates
• Analyzing the impact of probiotic supplementation on high-fat diet-induced metabolic disorders based on rat model outcomes
• Investigating gut microbiota modulation by probiotics based on genus-level structural changes and short-chain fatty acid correlations

Strengths

• Provides specific quantitative results, including a cholesterol-lowering rate of 71.2 ± 0.9% and DPPH scavenging rate of 84.6 ± 1.3%
• Documents a multi-faceted experimental design combining in vitro assays with an in vivo rat model
• Includes detailed measurements of probiotic effects on rats, such as reductions in weight gain (22.01%) and liver enzymes (26.10-26.27%)

Limitations

• The dataset is a 217.8 KB DOCX file containing a research article, not structured data; column-level documentation is absent
• Row count is unknown, which may limit suitability assessment for direct data analysis
• The data reflects a single, controlled animal study; generalizability to other contexts may be limited

Provenance

Source

figshare

Collection Method

Experimental laboratory study involving in vitro screening and in vivo rat model testing.

Freshness

Last updated 2026-06-04 05:40:29