Prognostic Significance of Lymphocyte PD-1 Expression in Liver Cirrhosis with Sepsis

86 patients with liver cirrhosis complicated by sepsis were prospectively enrolled at Beijing You’an Hospital between June 2023 and May 2024. The dataset includes flow cytometric analysis of PD-1 expression on lymphocyte subsets, clinical scoring systems, and 28-day mortality outcomes. The study was authored by Zhao Liu and shared under a CC-BY-4.0 license.

Use Cases

• Predicting 28-day mortality based on lymphocyte PD-1 expression levels.
• Evaluating the combined prognostic value of immune markers and clinical scores like Child-Pugh and CLIF-SOFA.
• Analyzing correlations between immune exhaustion markers and disease severity scores in septic cirrhosis.

Strengths

• Includes data from 86 prospectively enrolled patients.
• Contains flow cytometric analysis of PD-1 expression on CD3+, CD4+, and CD8+ lymphocyte subsets.
• Links biomarker data with established clinical scoring systems and 28-day mortality outcomes.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data is from a single hospital, which may reflect geographic or institutional bias.

Provenance

Source

Beijing You’an Hospital

Collection Method

Prospective clinical study with flow cytometric analysis.

Time Range

June 2023 to May 2024

Freshness

Last updated 2026-05-13 05:51:56; freshness should be verified.

Geography

China