Rat Hippocampus and Prefrontal Cortex Mitochondrial Network Morphology

Quantitative data on mitochondrial network architecture in neurites and somata from rat prefrontal cortex and hippocampus. The dataset includes volume fractions, individual mitochondrial volumes, and shape distributions derived from automated segmentation of volumetric electron microscopy data. Author Lu Wang published the data on figshare under a CC-BY-4.0 license, with a last update in April 2026.

Use Cases

• Modeling mitochondrial distribution heterogeneity based on reported volume fractions in neurites versus somata
• Analyzing the prevalence of specific mitochondrial shapes (e.g., oval, rod, linear) based on the described quantitative results
• Studying the structure of nanotunnels connecting mitochondria based on the reported segment dimensions and frequency

Strengths

• Includes specific quantitative metrics, such as a 7.2% mitochondrial volume fraction in PFC neurites and 2.9% in somata
• Reports detailed morphological statistics, including mean individual mitochondrial volumes (e.g., 0.11 μm³ for neuritic mitochondria in PFC) and shape percentages (e.g., ~91% oval or rod)
• Data is derived from an automated segmentation pipeline based on an attention-enhanced 3D U-Net applied to volumetric EM data

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The dataset is small (769.0 KB), suggesting limited scope or aggregated summary statistics rather than raw observations

Provenance

Source

figshare

Collection Method

Automated tape-collecting ultramicrotome scanning electron microscopy (ATUM-SEM) and an automated segmentation pipeline using an attention-enhanced 3D U-Net.

Freshness

Last updated 2026-04-21 04:21:57; freshness should be verified

Geography

Rat brain samples (prefrontal cortex and hippocampus CA1 stratum radiatum).