Rat Liver Transcriptomics and Lipid Profiles from Maternal Dietary Restriction Study

Supplementary file 1 from a study investigating the effects of maternal dietary restriction on rat offspring growth and lipid metabolism. The dataset includes body weight, body length, serum lipid profiles, and liver transcriptomic analysis results from Sprague-Dawley rats. It was authored by Xin Liu and last updated on June 4, 2026.

Use Cases

• Analyzing gene expression changes in lipid metabolism pathways based on transcriptomic results.
• Investigating correlations between serum lipid profiles (TG, HDL-C) and growth parameters in a rat model.
• Validating in vitro findings on LPL overexpression and its effect on lipogenic genes ACACA and SCD.

Strengths

• Includes transcriptomic analysis from Agilent microarrays, providing gene-level data.
• Contains longitudinal measurements of body weight, body length, and serum lipids from postnatal day 1 to day 21.
• Data is associated with a peer-reviewed research study with a clear experimental design.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small (224.7 KB), indicating limited scope.

Provenance

Source

figshare

Collection Method

Data was generated from an experimental rat model of extrauterine growth restriction (EUGR) established by maternal dietary restriction, followed by serum analysis and liver transcriptomics.

Freshness

Last updated 2026-06-04 05:32:55; freshness should be verified.