Rat Metabolomics Data from Branched-Chain Amino Acid Timing Study

18 male Sprague–Dawley rats were fed diets redistributing branched-chain amino acids across circadian phases for 12 weeks. Untargeted metabolomics data for liver and skeletal muscle, plasma lipids, and growth trajectories were collected by Kuai Yu and published on figshare in April 2026. The liver metabolome showed the strongest group separation, driven by lipid-related features.

Use Cases

• Analyze hepatic metabolic pathway enrichment based on untargeted liver metabolome data mentioned in the description
• Compare plasma lipid profiles based on LDL-C measurements across different feeding schedules
• Model growth trajectory uniformity based on residual variance data from the study
• Investigate skeletal muscle mTORC1 signaling based on S6 phosphorylation endpoint data
• Evaluate hepatic antioxidant indices based on total superoxide dismutase activity and glutathione pathway enrichment

Strengths

• Data includes untargeted metabolomics for two tissues (liver and skeletal muscle)
• Study design involved 18 rats over a 12-week period
• Multiple endpoints measured: plasma lipids, growth trajectories, antioxidant indices, and pathway enrichment

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data is from a specific animal model (Sprague–Dawley rats) and may not generalize directly

Provenance

Source

figshare

Collection Method

Experimental data from a controlled animal nutrition study.

Time Range

Study duration of 12 weeks.

Freshness

Last updated 2026-04-09 05:14:47