Protocol for a Systematic Review on Neutropenic Diets in Stem Cell Transplant Recipients

A protocol document outlines a planned systematic review and meta-analysis to evaluate the benefits and harms of neutropenic diets compared to less restrictive dietary approaches in patients undergoing haematopoietic stem cell transplantation. The review, registered with PROSPERO (CRD420251162724), will search multiple databases from inception without language or date restrictions. The primary outcomes include infection rates, acute graft-versus-host disease, nutritional status, time to neutrophil recovery, and patient satisfaction.

Use Cases

• Conducting a systematic review based on the detailed methodology and search strategy
• Assessing the evidence base for dietary interventions in immunocompromised patients based on the described outcomes
• Informing clinical practice guidelines for post-transplant care based on the planned analysis of benefits and harms

Strengths

• The protocol is registered with PROSPERO (CRD420251162724), indicating a structured and transparent research plan
• The search strategy includes eight major databases and registries (MEDLINE, Embase, CENTRAL, Web of Science, CINAHL, Scopus, ClinicalTrials.gov, WHO ICTRP) from inception

Limitations

• The dataset is a 15.9 KB DOCX protocol document, not the actual review data or results
• Column-level documentation is absent; the file contains methodological text rather than structured data fields

Provenance

Source

figshare

Collection Method

Authored protocol document

Freshness

Last updated 2026-05-26 04:39:03