Supplementary file 1_Sex-specific differences in basilar artery vasospasm after subarachno

Supplementary file 1_Sex-specific differences in basilar artery vasospasm after subarachnoid hemorrhage: evidence from a rabbit model.docx is a research document authored by İskender Samet Daltaban, last updated on June 3, 2026. It details a controlled preclinical study using 24 New Zealand White rabbits to investigate sex-specific differences in basilar artery vasospasm following subarachnoid hemorrhage.

Use Cases

• Analyzing sex-specific differences in vasospasm severity based on the Vasospasm Index (VSI) measurements.
• Comparing histopathological outcomes such as smooth muscle contraction and endothelial integrity between male and female subjects.
• Investigating the relationship between biological sex and secondary injury outcomes in a controlled subarachnoid hemorrhage model.

Strengths

• The study uses a randomized, controlled rabbit model with 12 male and 12 female subjects, allowing for direct sex comparisons.
• Quantitative assessment is performed using the Vasospasm Index (VSI), with reported values of 2.34 ± 0.63 for males and 1.27 ± 0.49 for females.
• Results are corroborated by blinded qualitative histopathological scoring of multiple vascular features.

Limitations

• The dataset is a 187.7 KB DOCX file, indicating a limited scope primarily containing textual results and analysis rather than raw data tables.
• Column-level documentation and sample data are unavailable, making direct computational analysis difficult without manual extraction.
• The data is derived from a single preclinical animal model, which may limit direct translation to human clinical contexts.

Provenance

Source

İskender Samet Daltaban

Collection Method

Data was generated from a randomized, controlled rabbit model experiment where subarachnoid hemorrhage was induced by cisterna magna injection of autologous blood.

Freshness

Last updated 2026-06-03 04:26:46