Pediatric Acute Phosphate Nephropathy Case Report and Literature Review

A 2.6 MB document details the first reported case of acute phosphate nephropathy in a child, a 9-year and 4-month-old patient. The case report includes clinical manifestations like frequent urination and foamy urine, lab results for blood calcium and creatinine, and treatment outcomes. It is authored by Siyi Zhu and includes a review of recent literature on the disease's etiology and treatment.

Use Cases

• Analyze the clinical presentation of frequent urination, urgency, and foamy urine in the context of pediatric renal disease.
• Review lab result trends for blood calcium, urinary calcium, and blood creatinine before and after combined traditional Chinese and Western medicine treatment.
• Study the reported etiology, specifically the long-term use of alpha-calcidol, in relation to calcium phosphate crystal deposition.
• Examine renal biopsy findings describing significant deposition of calcium phosphate salts in the renal tubular interstitium.

Strengths

• Documents the first reported pediatric case of acute phosphate nephropathy, a rare condition.
• Includes specific patient data: age (9 years, 4 months), symptoms, and lab values for blood calcium and creatinine.
• Provides a literature review discussing disease etiology, pathogenic mechanisms, and treatment strategies.
• Released under a permissive CC BY 4.0 license for reuse.

Limitations

• Contains data from a single case report (n=1), limiting statistical generalizability.
• The primary data is embedded in a narrative DOCX file, requiring manual extraction for quantitative analysis.
• No structured tabular data (rows/columns) is provided; all information is in textual format.

Provenance

Source

figshare, authored by Siyi Zhu.

Collection Method

Clinical case report and literature review.

Time Range

Case report timeframe unspecified; literature review includes recent publications.

Freshness

Last updated March 25, 2026.