UK Biobank Beverage Intake and Kidney Stone Risk with Genetic Susceptibility

191,863 UK Biobank participants were followed for 13.5 years to investigate associations between beverage consumption and kidney stone disease. Binxian Ye authored this study, which found a 51% higher risk for high sugar-sweetened beverage intake. The dataset likely contains dietary recall data, genetic risk scores, and incident case outcomes.

Use Cases

• Analyze dose-response relationships between beverage categories and kidney stone incidence based on the reported hazard ratios.
• Investigate gene-environment interactions based on the polygenic risk score and stratified analyses described.
• Model longitudinal health outcomes based on the 13.5-year follow-up period mentioned.
• Validate dietary assessment methods for large cohort studies based on the web-based 24-hour recall methodology.

Strengths

• Large cohort size of 191,863 participants.
• Longitudinal design with a mean follow-up of 13.5 years.
• Includes genetic susceptibility data via a polygenic risk score comprising 22 SNPs.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The primary data file is a DOCX document, which may require extraction of underlying data.

Provenance

Source

UK Biobank

Collection Method

Prospective cohort study using web-based 24-hour dietary recalls.

Time Range

Follow-up period of 13.5 years; dietary assessment from 2009–2012.

Freshness

Last updated 2026-05-21 04:19:17; freshness should be verified.

Geography

United Kingdom