Mouse Gut Microbiota and Metabolite Data for DSS-Induced Colitis Study

A multi-omics dataset from a murine colitis study investigates the effects of Taoling Yuyang Decoction. Dongyang Liu authored this dataset, which was last updated on April 29, 2026. It includes measurements of body weight, disease activity index, oxidative stress markers, cytokine levels, tight junction protein expression, and 16S rDNA sequencing results.

Use Cases

• Analyze gut microbiota composition changes based on 16S rDNA sequencing data mentioned in the description
• Correlate metabolite levels with disease severity based on fecal metabolomics and SCFA measurements
• Model the relationship between oxidative stress markers and intestinal barrier function based on MDA, GSH-Px, SOD, and tight junction protein data

Strengths

• Includes multi-omics data from 16S rDNA sequencing and metabolomics
• Contains measurements from five distinct experimental groups with eight mice per group
• Quantifies multiple biological endpoints: disease activity, oxidative stress, cytokines, and barrier proteins

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data is from a single mouse model study, limiting generalizability

Provenance

Source

figshare

Collection Method

Experimental data collected from a DSS-induced mouse model of colitis using commercial kits, ELISA, qPCR, immunohistochemistry, and sequencing.

Freshness

Last updated 2026-04-29 05:57:48; freshness should be verified