Acute Physiology Scores and Sepsis in ICU Non-Surviving IBD Patients

A retrospective cohort study from the eICU-CRD database analyzes 190 adult inflammatory bowel disease patients who died during ICU admission. It examines the association between Acute Physiology Score (APS) and sepsis, finding APS independently associated with sepsis risk. The dataset was authored by Chenyang Li and last updated on 2026-06-03.

Use Cases

• Modeling sepsis risk based on Acute Physiology Score in critically ill IBD patients.
• Investigating correlations between APS and metabolic markers like anion gap, lactate, and bicarbonate.
• Evaluating predictive performance of APS for sepsis in demographic subgroups like elderly or male patients.
• Training or benchmarking machine learning models for ICU mortality prediction using clinical severity scores.

Strengths

• Dataset is derived from the eICU-CRD, a multi-center intensive care database.
• Analysis includes 190 patient records with detailed statistical results (e.g., OR=1.027, p=0.004).
• Study employs multiple analytical methods including weighted logistic regression, restricted cubic splines, and XGBoost with SHAP.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The study's sample size is small (190 patients) and findings are hypothesis-generating, as noted by the authors.

Provenance

Source

eICU-CRD database

Collection Method

Retrospective cohort study

Freshness

Last updated 2026-06-03 04:48:51; freshness should be verified.