Supplementary file 1_The delirium dichotomy of remimazolam: a differential risk profile fo

Ziyu Zhu published a systematic review and meta-analysis on figshare in May 2026. The document synthesizes evidence from 30 clinical trials, including 25 RCTs, to assess the association between the anesthetic remimazolam and postoperative or emergence delirium. The analysis includes data on 5,561 patients and reports outcomes like delirium incidence, postoperative nausea and vomiting, extubation time, and hospital length of stay.

Use Cases

• Comparing delirium risk between anesthetic regimens based on the meta-analysis results
• Investigating the differential risk for emergence delirium versus postoperative delirium based on the study's dichotomy
• Analyzing secondary outcomes like postoperative nausea and vomiting incidence mentioned in the description
• Assessing the effect of anesthesia type and patient age on outcomes via subgroup analysis

Strengths

• Analysis is based on 30 clinical trials with data from 5,561 patients
• Includes multiple outcome measures: primary (delirium incidence) and secondary (PONV, respiratory depression, extubation time, hospital stay)
• Conducts subgroup and meta-regression analyses to explore sources of heterogeneity

Limitations

• Dataset is a single DOCX document; underlying trial-level data is not provided
• Row and column structure of the source data is unknown
• Freshness should be verified; last updated 2026-05-11 05:28:38

Provenance

Source

Ziyu Zhu

Collection Method

Systematic review and meta-analysis of published clinical trials.

Time Range

Literature search up to December 10, 2025.

Freshness

Last updated 2026-05-11 05:28:38