Gene Editing Therapy Publications, 2005-2025 Bibliometric Analysis

1,571 peer-reviewed articles and reviews on gene editing therapies for human genetic diseases, published between 2005 and 2025. The data was analyzed by Xinhao Zhou using CiteSpace and VOSviewer to map collaboration networks and thematic clusters. Publication growth is described in three phases: engineered nucleases (2005–2012), CRISPR revolution (2013–2018), and precision translation (2019–2025).

Use Cases

• Analyze publication trends and growth phases in gene editing research based on the described three-phase exponential growth.
• Map institutional collaboration networks based on the mention of key hubs like Harvard and the University of California.
• Identify primary disease targets for gene editing based on the focus on hematologic disorders like sickle cell disease and β-thalassemia.
• Study emerging research frontiers based on described trends like base editing, prime editing, and AI-assisted design.

Strengths

• Analysis is based on 1,571 peer-reviewed articles and reviews from Web of Science and Scopus.
• Covers a defined 20-year time range from 2005 to 2025.
• Identifies specific leading disease targets and institutional hubs.

Limitations

• The dataset is a single 82.6 KB DOCX file, indicating limited raw data scope.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data may reflect publication bias inherent to the selected bibliographic databases.

Provenance

Source

Articles retrieved from Web of Science Core Collection and Scopus.

Collection Method

Science mapping conducted using CiteSpace and VOSviewer.

Time Range

2005 to 2025

Freshness

Last updated 2026-06-03 04:26:48

Geography

Global, with noted dominance by the United States and China.