U.S. Acute Myocardial Infarction Mortality Trends and Disparities, 1999–2023

3,255,707 AMI-related deaths were analyzed from CDC WONDER data. The dataset contains age-adjusted mortality rates, annual percent changes, and breakdowns by sex, race, and urban-rural classification from 1999 to 2023. It was authored by Jiayin Zhu and last updated in May 2026.

Use Cases

• Analyzing long-term mortality trends based on age-adjusted mortality rates (AAMRs) and joinpoint regression results.
• Investigating demographic disparities based on sex and race breakdowns of mortality rates.
• Studying geographic health inequities based on urban-rural mortality comparisons.
• Validating public health interventions by examining phase-specific mortality changes, such as the plateau from 2018–2021.

Strengths

• Analyzes 3,255,707 death records over a 24-year period (1999–2023).
• Provides age-adjusted mortality rates with confidence intervals and annual percent change calculations.
• Includes sensitivity analysis using both underlying and multiple cause of death data for robustness.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The 179.5 KB file size suggests a highly aggregated or summary-level dataset, not individual-level records.

Provenance

Source

CDC WONDER underlying cause of death and Multiple Cause of Death datasets.

Collection Method

Death records listing AMI (ICD-10: I21–I22) as cause of death were retrieved; rates were calculated and standardized to the 2000 US population.

Time Range

1999 to 2023

Freshness

Last updated 2026-05-19 05:38:35

Geography

United States