Supplementary file 1_Use of oXiris® vs standard AN69ST filters in sepsis-associated acute

David Yepes Gómez published a retrospective matched cohort study comparing oXiris® and standard AN69ST hemofilters in patients with septic shock and acute kidney injury requiring continuous renal replacement therapy. The dataset includes 81 matched patients from a tertiary ICU in Medellín, Colombia, between November 2020 and May 2023, with outcomes tracked over 28 days. It contains results on mortality, ventilator-free days, ICU-free days, and early physiological changes.

Use Cases

• Compare 28-day mortality outcomes based on hemofilter type used during continuous renal replacement therapy.
• Analyze secondary outcomes like ventilator-free days and ICU length of stay based on patient treatment groups.
• Assess early physiological changes in SOFA score, lactate, and C-reactive protein levels between treatment cohorts.
• Perform propensity score matching or inverse probability weighting analyses on critical care patient data.

Strengths

• Includes data from 81 matched patients, providing a basis for comparative analysis.
• Covers multiple clinical outcomes: primary 28-day mortality, plus secondary outcomes like ventilator-free days and ICU length of stay.
• Employs a matched cohort design with propensity scores based on age, SOFA score, time to CRRT, and infection source.
• Contains prespecified sensitivity analyses excluding COVID-19 cases and using inverse probability of treatment weighting.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect geographic and temporal bias inherent to a single-center study in Medellín, Colombia.

Provenance

Source

David Yepes Gómez

Collection Method

Retrospective matched cohort study within a dynamic cohort of consecutive adults.

Time Range

November 2020 - May 2023

Freshness

Last updated 2026-05-12 05:42:20; freshness should be verified.

Geography

Tertiary ICU in Medellín, Colombia