Supplementary file 1_Vitamin D status and Helicobacter pylori infection: clinical associat

A 2026 cross-sectional study of 502 Lebanese adults (323 females, 179 males) by Said El Shamieh, investigating associations between vitamin D deficiency and Helicobacter pylori infection. An exploratory untargeted metabolomics sub-study of 50 participants identified lipid pathway differences, including sphingolipid and glycerophospholipid metabolism.

Use Cases

• Modeling H. pylori infection risk based on vitamin D status and demographic variables mentioned in the description
• Exploring metabolic pathway differences (e.g., sphingolipid metabolism) associated with vitamin D deficiency
• Conducting secondary analysis on the association between serum iron levels and H. pylori infection status

Strengths

• Multivariable analysis includes 502 participants with clinical and biochemical variables
• Exploratory metabolomics sub-study of 50 participants with pathway enrichment results (e.g., sphingolipid impact=0.735)
• Strong statistical associations reported (e.g., p < 10^-23 for vitamin D deficiency frequency)

Limitations

• Row count for the main dataset is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• The metabolomics sub-study is exploratory with a small sample size (n=50)

Provenance

Source

figshare, author Said El Shamieh

Collection Method

Cross-sectional study with demographic, clinical, and biochemical data collection; untargeted metabolomics performed on a sub-cohort.

Freshness

Last updated 2026-06-01 05:36:56

Geography

Lebanon