Xingpi Yanger Granule Meta-Analysis for Nocturnal Enuresis Treatment

12 randomized controlled trials involving 1,138 patients form the basis of this systematic review and meta-analysis. Ru-Ping Zhao authored this document, which analyzes the efficacy and safety of combining Xingpi Yanger Granule with conventional medication for pediatric nocturnal enuresis. The review protocol was registered on PROSPERO and the analysis was last updated in May 2026.

Use Cases

• Evaluating the clinical efficacy of a traditional Chinese medicine formula based on pooled results from 12 RCTs
• Assessing the safety profile of a combined therapy regimen based on adverse reaction incidence data
• Analyzing biochemical correlates of treatment response based on reported antidiuretic hormone and urinary osmolality levels

Strengths

• Analysis is based on 12 randomized controlled trials with a total of 1,138 patients.
• The review employed multiple analytical methods including meta-analysis, sensitivity analysis, and Trial Sequential Analysis (TSA).
• The protocol was registered on PROSPERO (CRD420251156842), indicating a structured, pre-defined methodology.

Limitations

• The evidence is described as 'limited in scope' and rated as 'low to moderate quality' by the authors.
• The dataset is a single 260.3 KB DOCX file; its internal structure and any underlying data tables are not described.
• Column-level documentation is absent; field semantics must be inferred after download.

Provenance

Source

Ru-Ping Zhao

Collection Method

Systematic literature search across CNKI, Wanfang, CBM, VIP, PubMed, Embase, Cochrane Library, and Web of Science.

Time Range

From database inception up to August 2025.

Freshness

Last updated 2026-05-12 05:42:29

Geography

Likely focuses on trials conducted in China, given the databases searched, but not explicitly stated.