Osteoporosis Study Data on 5-Methoxyresorcinol Effects in Mice

Supplementary data from a study evaluating the therapeutic potential of 5-methoxyresorcinol (MR) for osteoporosis. The dataset likely contains results from network pharmacology analysis identifying 107 MR targets and 8,060 osteoporosis genes, and in vitro/in vivo experiments using an ovariectomized mouse model. It was authored by Maosheng Yang and published on figshare in May 2026.

Use Cases

• Analyze overlapping targets between a compound and a disease based on the network pharmacology results mentioned in the description
• Study dose-dependent effects on osteoclast differentiation based on the in vitro experiment results described
• Evaluate bone microarchitecture improvements based on the micro-CT and histological analysis data from the OVX mouse model
• Investigate signaling pathway inhibition based on the described PI3K–AKT–GSK3β pathway and ROS homeostasis data

Strengths

• Includes results from multiple methodological approaches: network pharmacology, in vitro cell assays, and an in vivo mouse model
• Specific quantitative results are reported, such as 107 potential MR targets and 50 overlapping genes
• Published under a CC-BY-4.0 license, allowing for open reuse and redistribution

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The dataset is very small (200 KB), suggesting it contains summary or processed results rather than raw experimental data

Provenance

Source

figshare

Collection Method

Likely contains processed results from network pharmacology analysis and laboratory experiments.

Freshness

Last updated 2026-05-18 04:17:01; freshness should be verified