Gut Microbiome and Metabolome Profiles of Hypertensive Patients from Daqing and Haikou

Shotgun metagenomic sequencing and untargeted metabolomics data from fecal samples of 60 hypertensive patients collected between May and December 2024. The study compares microbial and metabolic profiles from patients in two Chinese cities with distinct climates: Daqing (middle-temperate) and Haikou (tropical). The dataset was authored by Shuyue Liu and published on figshare.

Use Cases

• Identify differentially abundant microbial genera based on geographic grouping.
• Analyze dysregulated metabolic pathways such as glycerophospholipid metabolism and ABC transporters.
• Build logistic regression models for geographic classification using microbial features.
• Explore correlations between specific differential microbes and metabolites like 15-HETE and ginsenoside Rg3.

Strengths

• Includes data from 60 patients (28 from Daqing, 32 from Haikou) with shotgun metagenomic sequencing.
• Identified 34 differentially abundant genera and 38 differentially abundant metabolites.
• Analysis adjusted for confounding variables including age, BMI, smoking, and drinking status.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is 1.2 MB, suggesting a relatively small scale.

Provenance

Source

figshare

Collection Method

Cross-sectional study using shotgun metagenomic sequencing and untargeted metabolomics on fecal samples.

Time Range

Data collected between May and December 2024.

Freshness

Last updated 2026-05-22 05:37:11; freshness should be verified.

Geography

Patients from Daqing (middle-temperate climate) and Haikou (tropical climate) in China.