Mouse Data on Caffeine Attenuating Cisplatin-Induced Cognitive Dysfunction

Supplementary file 2_Caffeine attenuates cisplatin induced microglial reactivity and cognitive dysfunction.xlsx contains data from a mouse model study of chemotherapy-induced cognitive impairments. The dataset, authored by Alfredo Oliveros and shared under a CC-BY-4.0 license, likely contains measurements related to microglial morphology, body weight, physical recovery, motor function, hippocampal dendritic spine density, and neurogenesis. It was last updated on May 13, 2026.

Use Cases

• Analyze microglial morphological changes based on process extension and branching complexity data mentioned in the description
• Model the relationship between body-weight loss, physical recovery, and motor dysfunction following cisplatin treatment
• Investigate correlations between hippocampal dendritic spine density, neurogenesis, and memory performance in a chemotherapy model

Strengths

• Dataset is openly licensed under CC-BY-4.0, allowing for broad reuse.
• The study design investigates a specific neurobiological mechanism (A2AR-mediated microglial priming) in a defined model of chemobrain.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small (177.8 KB), indicating a limited scope of observations.

Provenance

Source

figshare

Collection Method

Data collected from a controlled laboratory experiment using a mouse model treated with cisplatin and caffeine.

Freshness

Last updated 2026-05-13 05:35:56; freshness should be verified.