Molecular Profile of Granular Cell Astrocytoma: Two Clinical Case Reports

Melanie Jensen's 2026 figshare document presents molecular and clinical data for two rare granular cell astrocytoma (GCA) cases. The data includes clinical, histopathological, and molecular profiles from DNA methylation, targeted sequencing, and whole genome sequencing. Both cases, from patients aged 63 and 54, were molecularly classified as IDH-wildtype glioblastoma, mesenchymal subtype.

Use Cases

• Correlating tumor morphology with molecular subtype based on methylation profiling data mentioned in the description.
• Identifying shared genomic alterations (e.g., chromosome +7/-10, CDKN2A/B deletion) in rare glioma variants.
• Studying clinical outcomes (e.g., recurrence, survival) in relation to integrated molecular testing results.

Strengths

• Includes detailed molecular profiling data from DNA methylation, targeted NGS, and whole genome sequencing.
• Provides integrated clinical, histopathological, and molecular data for two well-documented cases.
• Published under a CC-BY-4.0 license, permitting reuse and redistribution.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (17.8 KB), containing only two case reports.

Provenance

Source

figshare, author Melanie Jensen.

Collection Method

Clinical case report data from a neuropathology department, generated via molecular profiling.

Time Range

Case reports from 2026.

Freshness

Last updated 2026-05-04 05:01:13; freshness should be verified.

Geography

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