Stickleback Transcriptomic Responses to Immune Stimuli Across Populations

Transcriptomic data from lab-reared threespine stickleback fish from three populations with varying susceptibility to the cestode parasite Schistocephalus solidus. The dataset compares gene expression changes in response to immune stimuli including alum, cestode protein, and a control injection. It was authored by Lauren E. Fuess and last updated on 2026-03-18.

Use Cases

• Identify shared and population-specific gene expression patterns based on exposure to different immune stimuli.
• Analyze the role of fibrosis-associated gene regulation in the evolution of parasite resistance.
• Compare constitutive expression levels of immune-related genes across stickleback populations with varying susceptibility.
• Study the evolutionary co-option of tissue damage response pathways for parasite defense.

Strengths

• Dataset is openly licensed under CC-BY-4.0.
• Focus on a well-studied evolutionary model system (threespine stickleback) encountering a novel parasite.
• Compares transcriptomic responses across three distinct populations with known phenotypic differences in susceptibility.

Limitations

• Dataset is small at 31.3 KB, indicating limited scope.
• Row count and column-level documentation are unknown, requiring manual inspection after download.
• Data is from a controlled lab experiment; ecological validity in wild populations is unknown.

Provenance

Source

Lauren E. Fuess via figshare.

Collection Method

Transcriptomic analysis of lab-reared sticklebacks exposed to immune stimuli.

Freshness

Last updated 2026-03-18 07:36:44.