Acupuncture Trial Protocol for Post-Stroke Vascular Vertigo

234 patients with post-stroke vascular vertigo are enrolled in a multicenter, randomized controlled trial. The study protocol details a 3-week intervention comparing acupuncture, sham acupuncture, and active drug groups, with follow-ups at 8 and 20 weeks. Primary and secondary outcomes include the Dizziness Handicap Inventory, anxiety scales, health surveys, and multimodal MRI data.

Use Cases

• Analyze the relationship between Dizziness Handicap Inventory (DHI) scores and treatment group assignment (acupuncture, sham, drug) across 234 patients.
• Investigate correlations between Expectation Rating Scale (ERS) results and clinical efficacy outcomes like the SF-36 health survey.
• Compare safety profiles by examining adverse event records across the three intervention arms over the 20-week follow-up period.
• Explore central nervous system mechanisms by analyzing multimodal magnetic resonance imaging (MRI) data in relation to Dizziness and Anxiety Rating Scale (DARS) scores.

Strengths

• Protocol for a rigorously designed multicenter, double-blind, randomized controlled trial with 234 enrolled patients.
• Includes multiple clinical and mechanistic outcome measures: DHI, DARS, SF-36, TCD, and multimodal MRI.
• Study has received ethics approval (approval no. 2025KL-062) and is registered (ITMCTR2025001283).

Limitations

• Data is a 142.5 KB study protocol PDF, not the raw clinical trial results or a structured dataset.
• The sample size of 234 patients, while planned, may limit statistical power for subgroup analyses.
• Geographic coverage is limited to four subcenters, potentially introducing regional bias.

Provenance

Source

figshare, authored by Lina Pang.

Collection Method

Designed as a clinical trial protocol for a multicenter, randomized, sham-controlled study.

Time Range

Trial includes a 3-week treatment period and follow-ups at 8 and 20 weeks post-intervention.

Freshness

Protocol last updated on 2026-03-25.

Geography

Study conducted across four subcenters; specific locations not detailed.