Clinical Trial Protocol for Auditory Stimulation to Reduce Postoperative Sleep Disturbance

Xiaoxuan Hu's protocol document outlines a randomized controlled trial investigating intraoperative 40 Hz gamma frequency auditory stimulation for postoperative sleep disturbance. The trial plans to enroll 342 patients undergoing laparoscopic gynecological surgery, with primary and secondary outcomes including sleep incidence, anxiety scores, pain, and recovery metrics. The document was last updated on 2026-04 -16 and is shared under a CC-BY-4.0 license.

Use Cases

• Analyzing the design and outcome measures of a randomized controlled trial based on the detailed protocol description.
• Studying non-invasive perioperative strategies for sleep improvement based on the described auditory stimulation intervention.
• Extracting structured trial metadata for systematic reviews or meta-analyses based on the protocol's inclusion criteria and outcome definitions.

Strengths

• Protocol details a specific, double-blind trial design with 342 planned participants.
• Description explicitly lists 15 distinct secondary outcome measures including validated scales like AIS and HADS.
• Document includes a clinical trial registration identifier (ChiCTR2500110341) for verification.

Limitations

• The dataset is a 14.6 KB DOCX file, indicating a very small text document rather than a structured data release.
• Row count and column-level documentation are absent; data semantics must be inferred from the textual description.
• The data content is limited to the trial protocol; it does not contain the actual trial results or patient-level data.

Provenance

Source

figshare, author Xiaoxuan Hu.

Collection Method

Likely a manually authored clinical trial protocol document.

Time Range

Protocol publication date is 2026-04-16.

Freshness

Last updated 2026-04-16 05:16:37.

Geography

The trial registration is with the Chinese Clinical Trial Registry (ChiCTR), suggesting a likely focus on a Chinese patient population.