Fecal Shedding of Resistant Bacteria in Dairy Cows After Systemic Antibiotic Treatment

A randomized clinical trial dataset from figshare, authored by Juliano L. Gonçalves and last updated in April 2026. It records the long-term effects of systemic ceftiofur and ampicillin on the abundance and duration of fecal shedding of resistant Gram-negative bacteria in healthy dairy cows. The data includes weekly fecal sample measurements over an 11-week period following a 5-day treatment regimen.

Use Cases

• Modeling the temporal dynamics of antibiotic-resistant bacteria based on weekly fecal sampling over 11 weeks.
• Comparing treatment effects on bacterial abundance between antibiotic and control groups as described in the trial.
• Analyzing the proportion of resistant Gram-negative bacteria relative to total bacterial counts mentioned in the methods.
• Investigating correlations between antibiotic treatment and the prevalence of specific antimicrobial resistance gene classes like MLS, aminoglycoside, and tetracycline.

Strengths

• Data is from a controlled randomized clinical trial with three treatment groups (n=8 per group).
• Includes longitudinal measurements from weekly sampling over an 11-week period.
• Released under a permissive CC-BY-4.0 license for reuse.
• File size of 852.5 KB indicates a focused and likely manageable dataset.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for certain analyses.
• The dataset is small in scale (852.5 KB), indicating limited scope.

Provenance

Source

figshare

Collection Method

Randomized clinical trial with fecal samples collected, diluted, and plated on selective agar for bacterial enumeration.

Time Range

Weekly measurements over an 11-week period following treatment.

Freshness

Last updated 2026-04-30 14:30:37; freshness should be verified.

Geography

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