Influenza Virus Genomes from a Pediatric Hospital in Eastern China, 2024

Xiaoqing Sun's research dataset contains 425 influenza virus genomes sequenced from 490 antigen-positive pediatric specimens collected in Qidong, eastern China, in 2024. The data includes whole-genome sequences for co-circulating A/H1N1, A/H3N2, and B/Victoria lineages, with phylogenetic clade assignments and antiviral resistance markers. The dataset was last updated on 2026-04 16 and is shared under a CC-BY-4.0 license.

Use Cases

• Modeling influenza strain co-circulation patterns based on the reported subtype proportions and activity peaks.
• Analyzing genetic diversity and positive selection based on reported hemagglutinin (HA) and neuraminidase (NA) segment data.
• Tracking antiviral resistance markers based on the reported oseltamivir resistance (NA-H275Y) prevalence in A/H1N1 strains.
• Supporting local prevention strategy design based on the described genomic epidemiology from a specific pediatric population.

Strengths

• Contains 425 sequenced influenza genomes from a specific pediatric cohort of 490 specimens, yielding an 86.73% sequencing success rate.
• Provides detailed genetic characterization, including phylogenetic clade assignments for three circulating subtypes.
• Reports specific antiviral susceptibility data, including the frequency of the oseltamivir resistance marker NA-H275Y.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data is geographically limited to a single pediatric hospital in Qidong, eastern China.

Provenance

Source

Xiaoqing Sun, via figshare.

Collection Method

Influenza genome enrichment-based whole-genome sequencing performed on antigen-positive pediatric specimens.

Time Range

2024

Freshness

Last updated 2026-04-16 05:22:49; freshness should be verified.

Geography

Qidong, eastern China.