Mpox Coinfections and Clinical Manifestation in Africa: Systematic Review

Fabrice Zobel Lekeumo Cheuyem published a systematic review and meta-analysis on figshare in May 2026. The work analyzes 23 studies from Africa to describe the prevalence of HIV and VZV coinfections among confirmed mpox cases and characterize clinical presentation trends. It includes pooled prevalence estimates and explores heterogeneity across regions, study designs, and settings.

Use Cases

• Estimate pooled prevalence of VZV-mpox coinfection based on results from 10 studies
• Analyze heterogeneity in HIV-mpox coinfection prevalence across different study environments
• Compare clinical manifestations of mpox across viral clades I, Ia, and II
• Assess the burden of coinfections in hospital versus community-based settings

Strengths

• Includes results from 23 studies conducted across African countries
• Provides pooled prevalence estimates with confidence intervals for two specific coinfections
• Follows PRISMA guidelines and is registered in PROSPERO (CRD420251133960)

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data may reflect geographic bias inherent to the included studies

Provenance

Source

Fabrice Zobel Lekeumo Cheuyem

Collection Method

Systematic review and meta-analysis of observational studies from Africa, following PRISMA guidelines.

Time Range

Studies searched through 27 February 2025.

Freshness

Last updated 2026-05-07 04:37:21; freshness should be verified

Geography

Africa