Supplementary file 2_Potential efficacy and preliminary mechanistic insights of the Jianpi

A 12-month pilot study of 40 patients with rheumatoid arthritis complicated by sarcopenia-osteopenia, conducted by Weidong Liang and last updated in 2026. The dataset likely contains clinical outcomes, inflammatory markers, bone metabolism markers, and metabolomics results comparing a traditional Chinese medicine formula plus conventional therapy to conventional therapy alone. The study was registered under identifier ChiCTR2500106729.

Use Cases

• Compare clinical efficacy between treatment groups based on metrics like DAS28-ESR, ASMI, and BMD mentioned in the description.
• Analyze correlations between inflammatory markers (e.g., CRP, ESR, TNF-α) and bone-muscle metrics described in the results.
• Investigate preliminary metabolic pathway alterations based on the 14 pathways involving glucose, lipid, and amino acid metabolisms identified in the metabolomics analysis.
• Explore potential mechanistic insights for drug action based on in vitro findings related to PINK1/PARKIN and OPG/RANK pathways.

Strengths

• Includes data from a randomized controlled pilot study with 40 patients split into two groups.
• Contains a multi-faceted analysis combining clinical outcomes, laboratory markers, bone mineral density, muscle mass index, and metabolomics.
• Dataset is openly licensed under CC-BY-4.0, facilitating reuse and sharing.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 14.0 KB, indicating limited scope, likely containing summary results rather than raw patient-level data.

Provenance

Source

figshare, author Weidong Liang.

Collection Method

Data was collected from a 12-month randomized clinical pilot study.

Time Range

Study duration was 12 months; specific years of data collection are not provided.

Freshness

Last updated 2026-04-21 05:36:11; freshness should be verified.