Iodine Status and Handgrip Strength in a Northwestern Chinese Cohort

A cross-sectional study of 810 community-dwelling adults in Lanzhou, China, investigating the relationship between iodine nutritional status and low handgrip strength. The dataset was used to construct a predictive nomogram model integrating urinary iodine concentration, systolic blood pressure, and other clinical variables. The supplementary file was authored by Xiao Liu and last updated on 2026-04-14.

Use Cases

• Training a binary classification model to predict low handgrip strength based on clinical and demographic features.
• Analyzing the dose-response relationship between urinary iodine concentration and muscle strength outcomes.
• Validating a predictive nomogram model for early identification of individuals at high risk for sarcopenia.
• Conducting subgroup analysis to explore how associations vary by thyroid function status.

Strengths

• Includes data from 810 participants, split into training (n=568) and validation (n=242) cohorts.
• Model performance metrics are reported, including AUC (0.723 training, 0.662 validation) and Brier scores.
• The study identifies specific odds ratios for factors like age, sex, smoking, and iodine status.

Limitations

• Row count and column-level documentation are unknown, limiting suitability assessment.
• The cross-sectional design prevents causal inference, as noted in the description.
• Data is specific to a single cohort in Northwestern China, which may limit generalizability.

Provenance

Source

figshare, authored by Xiao Liu.

Collection Method

Cross-sectional study analyzing community-dwelling adults.

Freshness

Last updated 2026-04-14 04:19:50.

Geography

Lanzhou, China.